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Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy

Activated microglia are an important type of innate immune cell in the brain, and they secrete inflammatory cytokines into the extracellular milieu, exert neurotoxicity to surrounding neurons and are involved in the pathogenesis of many brain disorders. Quercetin (Qu), a natural flavonoid, is known...

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Detalles Bibliográficos
Autores principales: Han, Xiaojuan, Xu, Tianshu, Fang, Qijun, Zhang, Huajun, Yue, Lijun, Hu, Gang, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182123/
https://www.ncbi.nlm.nih.gov/pubmed/34082381
http://dx.doi.org/10.1016/j.redox.2021.102010