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Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of neuropathic and inflammatory pain in adult female mice

Cortical long-term potentiation (LTP) serves as a cellular model for chronic pain. As an important subtype of adenylyl cyclases (ACs), adenylyl cyclase subtype 1 (AC1) is critical for the induction of cortical LTP in the anterior cingulate cortex (ACC). Genetic deletion of AC1 or pharmacological inh...

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Detalles Bibliográficos
Autores principales: Zhou, Zhaoxiang, Shi, Wantong, Fan, Kexin, Xue, Man, Zhou, Sibo, Chen, Qi-Yu, Lu, Jing-Shan, Li, Xu-Hui, Zhuo, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182195/
https://www.ncbi.nlm.nih.gov/pubmed/34082635
http://dx.doi.org/10.1177/17448069211021698