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Cost‐effective purification process development for chimeric hepatitis B core (HBc) virus‐like particles assisted by molecular dynamic simulation

Inserting foreign epitopes to hepatitis B core (HBc) virus‐like particles (VLPs) could influence the molecular conformation and therefore vary the purification process. In this study, a cost‐effective purification process was developed for two chimeric HBc VLPs displaying Epstein–Barr nuclear antige...

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Detalles Bibliográficos
Autores principales: Zhang, Bingyang, Yin, Shuang, Wang, Yingli, Su, Zhiguo, Bi, Jingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182290/
https://www.ncbi.nlm.nih.gov/pubmed/34140854
http://dx.doi.org/10.1002/elsc.202000104