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Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus

Oncolytic viruses (OVs) represent promising therapeutic agents for cancer therapy by selective oncolysis and induction of anti-tumor immunity. OVs can be engineered to express tumor-associated antigens and immune-modulating agents to provoke stronger antitumor immunity. Here, we engineered vaccinia...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Jin, Chuan, Čančer, Matko, Wang, Hai, Ramachandran, Mohanraj, Yu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182386/
https://www.ncbi.nlm.nih.gov/pubmed/34141872
http://dx.doi.org/10.1016/j.omto.2021.04.016