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CD36 deficiency ameliorates drug-induced acute liver injury in mice

BACKGROUND: Acetaminophen (APAP) overdose causes hepatotoxicity and even acute liver failure. Recent studies indicate that sterile inflammation and innate immune cells may play important roles in damage-induced hepatocytes regeneration and liver repair. The scavenger receptor CD36 has its crucial fu...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Shi, Xiao, Su, Zhongping, Hu, Chao, Mu, Xianmin, Pan, Jinshun, Li, Mengjing, Teng, Fengmeng, Ling, Tao, Zhao, Ting, Xu, Che, Ji, Guozhong, You, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182905/
https://www.ncbi.nlm.nih.gov/pubmed/34092215
http://dx.doi.org/10.1186/s10020-021-00325-z