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Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases

BACKGROUND: Human T cell Leukemia virus type 1 (HTLV-I) is etiologically linked to adult T cell leukemia/lymphoma (ATL) and an inflammatory neurodegenerative disease called HTLV-I-associated myelopathy or tropical spastic paraparesis (HAM/TSP). The exact genetic or epigenetic events and/or environme...

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Detalles Bibliográficos
Autores principales: Bellon, Marcia, Bialuk, Izabela, Galli, Veronica, Bai, Xue-Tao, Farre, Lourdes, Bittencourt, Achilea, Marçais, Ambroise, Petrus, Michael N., Ratner, Lee, Waldmann, Thomas A., Asnafi, Vahid, Gessain, Antoine, Matsuoka, Masao, Franchini, Genoveffa, Hermine, Olivier, Watanabe, Toshiki, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183032/
https://www.ncbi.nlm.nih.gov/pubmed/34092254
http://dx.doi.org/10.1186/s12943-021-01370-2