Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening

During the repeated cycles of damage and repair in many muscle disorders, including Duchenne muscular dystrophy (DMD), the muscle stem cell (MuSC) pool becomes less efficient at responding to and repairing damage. The underlying mechanism of such stem cell dysfunction is not fully known. Here, we de...

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Detalles Bibliográficos
Autores principales: Tichy, Elisia D., Ma, Nuoying, Sidibe, David, Loro, Emanuele, Kocan, Jacob, Chen, Delia Z., Khurana, Tejvir S., Hasty, Paul, Mourkioti, Foteini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183356/
https://www.ncbi.nlm.nih.gov/pubmed/33979621
http://dx.doi.org/10.1016/j.celrep.2021.109098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183356/
https://www.ncbi.nlm.nih.gov/pubmed/33979621
http://dx.doi.org/10.1016/j.celrep.2021.109098

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