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Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening
During the repeated cycles of damage and repair in many muscle disorders, including Duchenne muscular dystrophy (DMD), the muscle stem cell (MuSC) pool becomes less efficient at responding to and repairing damage. The underlying mechanism of such stem cell dysfunction is not fully known. Here, we de...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183356/ https://www.ncbi.nlm.nih.gov/pubmed/33979621 http://dx.doi.org/10.1016/j.celrep.2021.109098 |