Anti-Seizure Activity of 1-Adamantane Carboxylic Acid in Common Experimental Seizure Models: Role of Benzodiazepine-GABA(A) Receptors

BACKGROUND: Despite introduction of modern antiepileptic drugs, 30% of epileptic patients are still drug resistant. Remarkable three-dimensional spatial structure of AdCA, yet the simplicity of the molecule, makes AdCA a promising lead compound. METHODS: Sedative/motor impairment and 24-h mortality...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghanbari, Elham, Gavzan, Hakimeh, Khoshkroodian, Bahar, Sayyah, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2021
Materias:
Full Length
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183385/
https://www.ncbi.nlm.nih.gov/pubmed/33653022
http://dx.doi.org/10.52547/ibj.25.3.213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183385/
https://www.ncbi.nlm.nih.gov/pubmed/33653022
http://dx.doi.org/10.52547/ibj.25.3.213

Ejemplares similares