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Latency-Associated Transcript-Derived MicroRNAs in Herpes Simplex Virus Type 1 Target SMAD3 and SMAD4 in TGF-β/Smad Signaling Pathway

BACKGROUND: During its latent infection, HSV-1 produces only a miRNA precursor called LAT, which encodes six distinct miRNAs. Recent studies have suggested that some of these miRNAs could target cellular mRNAs. One of the key cell signaling pathways that can be affected by HSV-1 is the TGF-β/Smad pa...

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Detalles Bibliográficos
Autores principales: Shojaei Jeshvaghani, Zahra, Arefian, Ehsan, Asgharpour, Sara, Soleimani, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183387/
https://www.ncbi.nlm.nih.gov/pubmed/33546553
http://dx.doi.org/10.52547/ibj.25.3.169