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HIV-1 infection and the lack of viral control are associated with greater expression of interleukin-21 receptor on CD8(+) T cells

OBJECTIVES: Interleukin-21 (IL-21) has been linked with the generation of virus-specific memory CD8(+) T cells following acute infection with HIV-1 and reduced exhaustion of CD8(+) T cells. IL-21 has also been implicated in the promotion of CD8(+) T-cell effector functions during viral infection. Li...

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Detalles Bibliográficos
Autores principales: Dalel, Jama, Ung, Seng K., Hayes, Peter, Black, S. Lucas, Joseph, Sarah, King, Deborah F., Makinde, Julia, Gilmour, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183476/
https://www.ncbi.nlm.nih.gov/pubmed/33710028
http://dx.doi.org/10.1097/QAD.0000000000002864