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A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation

The function of mucosal-associated invariant T (MAIT) cells highly depends on the mode of activation, either by recognition of bacterial metabolites via their T cell receptor (TCR) or in a TCR-independent manner via cytokines. The underlying molecular mechanisms are not entirely understood. To defin...

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Detalles Bibliográficos
Autores principales: Schubert, Kristin, Karkossa, Isabel, Schor, Jana, Engelmann, Beatrice, Steinheuer, Lisa Maria, Bruns, Tony, Rolle-Kampczyk, Ulrike, Hackermüller, Jörg, von Bergen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183572/
https://www.ncbi.nlm.nih.gov/pubmed/34108957
http://dx.doi.org/10.3389/fimmu.2021.616967