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Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts

The metabolic program of osteoblasts, the chief bone-making cells, remains incompletely understood. Here in murine calvarial cells, we establish that osteoblast differentiation under aerobic conditions is coupled with a marked increase in glucose consumption and lactate production but reduced oxygen...

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Detalles Bibliográficos
Autores principales: Lee, Wen-Chih, Ji, Xing, Nissim, Itzhak, Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183612/
https://www.ncbi.nlm.nih.gov/pubmed/32905773
http://dx.doi.org/10.1016/j.celrep.2020.108108