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Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts
The metabolic program of osteoblasts, the chief bone-making cells, remains incompletely understood. Here in murine calvarial cells, we establish that osteoblast differentiation under aerobic conditions is coupled with a marked increase in glucose consumption and lactate production but reduced oxygen...
Autores principales: | Lee, Wen-Chih, Ji, Xing, Nissim, Itzhak, Long, Fanxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183612/ https://www.ncbi.nlm.nih.gov/pubmed/32905773 http://dx.doi.org/10.1016/j.celrep.2020.108108 |
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