CryoDRGN: Reconstruction of heterogeneous cryo-EM structures using neural networks

Cryo-EM single-particle analysis has proven powerful in determining the structures of rigid macromolecules. However, many imaged protein complexes exhibit complex conformational and compositional heterogeneity that pose a major challenge to existing 3D reconstruction methods. Here, we present cryoDR...

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Detalles Bibliográficos
Autores principales: Zhong, Ellen D., Bepler, Tristan, Berger, Bonnie, Davis, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183613/
https://www.ncbi.nlm.nih.gov/pubmed/33542510
http://dx.doi.org/10.1038/s41592-020-01049-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183613/
https://www.ncbi.nlm.nih.gov/pubmed/33542510
http://dx.doi.org/10.1038/s41592-020-01049-4

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