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A nonsynonymous polymorphism (rs117179004, T392M) of hyaluronidase 1 (HYAL1) is associated with increased risk of idiopathic pulmonary fibrosis in Southern Han Chinese

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a genetic heterogeneous disease with high mortality and poor prognosis. Hyaluronidase 1 (HYAL1) was found to be upregulated in fibroblasts from IPF patients, and overexpression of HYAL1 could prevent human fetal lung fibroblast proliferation. Howeve...

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Detalles Bibliográficos
Autores principales: Liu, Juan, Deng, Yanhan, Wang, Zheng, Mo, Biwen, Wei, Jianghong, Cheng, Zhenshun, Peng, Qingzhen, Wei, Guang, Li, Jingping, Shu, Ying, Yang, Hua, Fang, Shirong, Luo, Guangwei, Yang, Shuo, Wang, Yingnan, Zhu, Jing, Yang, Jingping, Wu, Ming, Xu, Xuyan, Ge, Renying, Zhang, Xiaoju, Xiong, Weining, Wang, Xiaomei, Li, Zongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183947/
https://www.ncbi.nlm.nih.gov/pubmed/33942374
http://dx.doi.org/10.1002/jcla.23782