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Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10

The adaptive immune system serves as a potent and highly specific defense mechanism against pathogen infection. One component of this system, the effector T cell, facilitates pathogen clearance upon detection of specific antigens by the T cell receptor (TCR). A critical process in effector T cell ac...

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Detalles Bibliográficos
Autores principales: Campanello, Leonard, Traver, Maria K., Shroff, Hari, Schaefer, Brian C., Losert, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184007/
https://www.ncbi.nlm.nih.gov/pubmed/34014917
http://dx.doi.org/10.1371/journal.pcbi.1007986