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Whole-genome analysis of Malawian Plasmodium falciparum isolates identifies possible targets of allele-specific immunity to clinical malaria

Individuals acquire immunity to clinical malaria after repeated Plasmodium falciparum infections. Immunity to disease is thought to reflect the acquisition of a repertoire of responses to multiple alleles in diverse parasite antigens. In previous studies, we identified polymorphic sites within indiv...

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Detalles Bibliográficos
Autores principales: Shah, Zalak, Naung, Myo T., Moser, Kara A., Adams, Matthew, Buchwald, Andrea G., Dwivedi, Ankit, Ouattara, Amed, Seydel, Karl B., Mathanga, Don P., Barry, Alyssa E., Serre, David, Laufer, Miriam K., Silva, Joana C., Takala-Harrison, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184011/
https://www.ncbi.nlm.nih.gov/pubmed/34033654
http://dx.doi.org/10.1371/journal.pgen.1009576