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Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 75-residue integral membrane protein whose transmem...

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Detalles Bibliográficos
Autores principales: Park, Sang Ho, Siddiqi, Haley, Castro, Daniela V., De Angelis, Anna A., Oom, Aaron L., Stoneham, Charlotte A., Lewinski, Mary K., Clark, Alex E., Croker, Ben A., Carlin, Aaron F., Guatelli, John, Opella, Stanley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184013/
https://www.ncbi.nlm.nih.gov/pubmed/34003853
http://dx.doi.org/10.1371/journal.ppat.1009519