Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses

Macrophages initiate inflammatory responses via the transcription factor NFκB. The temporal pattern of NFκB activity determines which genes are expressed and thus, the type of response that ensues. Here, we examined how information about the stimulus is encoded in the dynamics of NFκB activity. We g...

Descripción completa

Detalles Bibliográficos
Autores principales: Adelaja, Adewunmi, Taylor, Brooks, Sheu, Katherine M., Liu, Yi, Luecke, Stefanie, Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184127/
https://www.ncbi.nlm.nih.gov/pubmed/33979588
http://dx.doi.org/10.1016/j.immuni.2021.04.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184127/
https://www.ncbi.nlm.nih.gov/pubmed/33979588
http://dx.doi.org/10.1016/j.immuni.2021.04.011

Ejemplares similares