Cargando…
Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses
Macrophages initiate inflammatory responses via the transcription factor NFκB. The temporal pattern of NFκB activity determines which genes are expressed and thus, the type of response that ensues. Here, we examined how information about the stimulus is encoded in the dynamics of NFκB activity. We g...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184127/ https://www.ncbi.nlm.nih.gov/pubmed/33979588 http://dx.doi.org/10.1016/j.immuni.2021.04.011 |