Two Novel Mutations of the NPM1 Gene in Syrian Adult Patients with Acute Myeloid Leukemia and Normal Karyotype

OBJECTIVE: Somatic mutations in exon 12 of the NPM1 gene is one of the most common genetic abnormalities in adult acute myeloid leukemia (AML), which is observed in 25-35% of AML patients and in 50-60% of patients with cytogenetically normal AML (CN-AML). METHODS: We performed Sanger sequencing of e...

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Detalles Bibliográficos
Autores principales: Alarbeed, Ismael F., Wafa, Abdulsamad, Moassass, Faten, Al-Halabi, Balssel, Alachkar, Walid, Aboukhamis, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184179/
https://www.ncbi.nlm.nih.gov/pubmed/33507703
http://dx.doi.org/10.31557/APJCP.2021.22.1.227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184179/
https://www.ncbi.nlm.nih.gov/pubmed/33507703
http://dx.doi.org/10.31557/APJCP.2021.22.1.227

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