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Aberrant Methylation of Tumour Suppressor Gene ADAM12 in Chronic Lympocytic Leukemia Patients: Application of Methylation Specific-PCR Technique

OBJECTIVE: Chronic Lymphocytic Leukemia (CLL) is a common leukemia among Caucasians but rare in Asians population. We postulated that aberrant methylation either hypermethylation or partial methylation might be one of the silencing mechanisms that inactivates the tumour suppressor genes in CLL. This...

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Detalles Bibliográficos
Autores principales: Mohamad, Amira, Hassan, Rosline, Husin, Azlan, Johan, Muhammad Farid, Sulong, Sarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184192/
https://www.ncbi.nlm.nih.gov/pubmed/33507683
http://dx.doi.org/10.31557/APJCP.2021.22.1.85