Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status

Paget’s disease of bone (PDB) is characterized by focal increases in disorganized bone remodeling. This study aims to characterize PDB-associated changes in DNA methylation profiles in patients’ blood. Meta-analysis of data from the discovery and cross-validation set, each comprising 116 PDB cases a...

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Detalles Bibliográficos
Autores principales: Diboun, Ilhame, Wani, Sachin, Ralston, Stuart H, Albagha, Omar ME
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184208/
https://www.ncbi.nlm.nih.gov/pubmed/33929316
http://dx.doi.org/10.7554/eLife.65715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184208/
https://www.ncbi.nlm.nih.gov/pubmed/33929316
http://dx.doi.org/10.7554/eLife.65715

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