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Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status
Paget’s disease of bone (PDB) is characterized by focal increases in disorganized bone remodeling. This study aims to characterize PDB-associated changes in DNA methylation profiles in patients’ blood. Meta-analysis of data from the discovery and cross-validation set, each comprising 116 PDB cases a...
| Autores principales: | , , , |
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| 格式: | Online 文件 Texto |
| 语言: | English |
| 出版: |
eLife Sciences Publications, Ltd
2021
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| 主题: | |
| 在线阅读: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184208/ https://www.ncbi.nlm.nih.gov/pubmed/33929316 http://dx.doi.org/10.7554/eLife.65715 |