Cargando…
Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens
The success of antimicrobial treatment is threatened by the evolution of drug resistance. Population genetic models are an important tool in mitigating that threat. However, most such models consider resistance emergence via a single mutational step. Here, we assembled experimental evidence that dru...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184216/ https://www.ncbi.nlm.nih.gov/pubmed/34001313 http://dx.doi.org/10.7554/eLife.64116 |