A computational approach for rational discovery of inhibitors for non-structural protein 1 of SARS-CoV-2

BACKGROUND: Non-structural protein 1 (Nsp1), a virulence agent of SARS-CoV-2, has emerged as an important target for drug discovery. Nsp1 shuts down the host gene function by associating with the 40S ribosomal subunit. METHODS: Molecular interactions, drug-likeness, physiochemical property predictio...

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Detalles Bibliográficos
Autores principales: Singh, Rahul, Bhardwaj, Vijay Kumar, Das, Pralay, Purohit, Rituraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184359/
https://www.ncbi.nlm.nih.gov/pubmed/34144270
http://dx.doi.org/10.1016/j.compbiomed.2021.104555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184359/
https://www.ncbi.nlm.nih.gov/pubmed/34144270
http://dx.doi.org/10.1016/j.compbiomed.2021.104555

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