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Attenuating glucose metabolism by Fbxw7 promotes Taxol sensitivity of colon cancer cells through downregulating NADPH oxidase 1 (Nox1)

BACKGROUND: Colorectal cancer (CRC), one of the most common malignancies worldwide, is associated with poor survival and has a high mortality rate. Taxol is a chemotherapeutic agent that has been clinically applied as a first-line drug against diverse cancers. Yet, development of drug resistance has...

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Detalles Bibliográficos
Autores principales: Wang, Hui-Peng, Chen, Wen-Jie, Shen, Jia-Men, Ye, Tao, Xie, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184419/
https://www.ncbi.nlm.nih.gov/pubmed/34164520
http://dx.doi.org/10.21037/atm-21-2076