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Absorption, metabolism, excretion, and safety of [(14)C]almonertinib in healthy Chinese subjects

BACKGROUND: Almonertinib Mesilate Tablets (HS-10296, Hansoh Pharma, Shanghai, China) is a novel and selective third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). A phase I study of almonertinib in patients with non-small cell lung cancer (NSCLC) demonstrated a lin...

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Detalles Bibliográficos
Autores principales: Zhou, Chen, Xie, Lijun, Liu, Wei, Zhang, Lingling, Zhou, Sufeng, Wang, Lu, Chen, Juan, Li, Huan, Zhao, Yuqing, Zhu, Bei, Ding, Sijia, Zhang, Chen, Shao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184462/
https://www.ncbi.nlm.nih.gov/pubmed/34164501
http://dx.doi.org/10.21037/atm-21-1606