NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8(+) T cell responses

The recognition of fungi by intracellular NOD-like receptors (NLRs) induces inflammasome assembly and activation. Although the NLRC4 inflammasome has been extensively studied in bacterial infections, its role during fungal infections is unclear. Paracoccidioidomycosis (PCM) is a pathogenic fungal di...

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Detalles Bibliográficos
Autores principales: Souza, Camila O.S., Ketelut-Carneiro, Natália, Milanezi, Cristiane M., Faccioli, Lúcia H., Gardinassi, Luiz G., Silva, João S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184506/
https://www.ncbi.nlm.nih.gov/pubmed/34142053
http://dx.doi.org/10.1016/j.isci.2021.102548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184506/
https://www.ncbi.nlm.nih.gov/pubmed/34142053
http://dx.doi.org/10.1016/j.isci.2021.102548

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