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NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8(+) T cell responses
The recognition of fungi by intracellular NOD-like receptors (NLRs) induces inflammasome assembly and activation. Although the NLRC4 inflammasome has been extensively studied in bacterial infections, its role during fungal infections is unclear. Paracoccidioidomycosis (PCM) is a pathogenic fungal di...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184506/ https://www.ncbi.nlm.nih.gov/pubmed/34142053 http://dx.doi.org/10.1016/j.isci.2021.102548 |