The Use of Subgroup Disproportionality Analyses to Explore the Sensitivity of a Global Database of Individual Case Safety Reports to Known Pharmacogenomic Risk Variants Common in Japan

INTRODUCTION: Genetic variations of enzymes that affect the pharmacokinetics and hence effects of medications differ between ethnicities, resulting in variation in the risk of adverse drug reactions (ADR) between different populations. Previous work has demonstrated that risk-group considerations ca...

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Detalles Bibliográficos
Autores principales: Wakao, Rika, Lönnstedt, Ingrid M., Aoki, Yasunori, Chandler, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184560/
https://www.ncbi.nlm.nih.gov/pubmed/33837924
http://dx.doi.org/10.1007/s40264-021-01063-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184560/
https://www.ncbi.nlm.nih.gov/pubmed/33837924
http://dx.doi.org/10.1007/s40264-021-01063-1

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