Cargando…

Uraemic extracellular vesicles augment osteogenic transdifferentiation of vascular smooth muscle cells via enhanced AKT signalling and PiT‐1 expression

Extracellular vesicles (EV) function as messengers between endothelial cells (EC) and vascular smooth muscle cells (VSMC). Since chronic kidney disease (CKD) increases the risk for vascular calcifications, we investigated whether EV derived from uraemic milieu‐stimulated EC and derived from uraemic...

Descripción completa

Detalles Bibliográficos
Autores principales: Freise, Christian, Querfeld, Uwe, Ludwig, Antje, Hamm, Bernd, Schnorr, Jörg, Taupitz, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184672/
https://www.ncbi.nlm.nih.gov/pubmed/33960650
http://dx.doi.org/10.1111/jcmm.16572