Cyclosporine A blocks autophagic flux in tubular epithelial cells by impairing TFEB‐mediated lysosomal function

Cyclosporine A (CsA) is an immunosuppressor widely used for the prevention of acute rejection during solid organ transplantation. However, severe nephrotoxicity has substantially limited its long‐term usage. Recently, an impaired autophagy pathway was suggested to be involved in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Li, Zhi‐hang, An, Ning, Huang, Xi‐jie, Yang, Chen, Wu, Hong‐luan, Chen, Xiao‐cui, Pan, Qing‐jun, Liu, Hua‐feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184677/
https://www.ncbi.nlm.nih.gov/pubmed/33949118
http://dx.doi.org/10.1111/jcmm.16593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184677/
https://www.ncbi.nlm.nih.gov/pubmed/33949118
http://dx.doi.org/10.1111/jcmm.16593

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