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Sestrin2 as a gatekeeper of cellular homeostasis: Physiological effects for the regulation of hypoxia‐related diseases

Sestrin2 (SESN2) is a conserved stress‐inducible protein (also known as hypoxia‐inducible gene 95 (HI95)) that is induced under hypoxic conditions. SESN2 represses the production of reactive oxygen species (ROS) and provides cytoprotection against various noxious stimuli, including hypoxia, oxidativ...

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Detalles Bibliográficos
Autores principales: Pan, Cunyao, Chen, Zhaoli, Li, Chao, Han, Tie, Liu, Hui, Wang, Xinxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184687/
https://www.ncbi.nlm.nih.gov/pubmed/33942488
http://dx.doi.org/10.1111/jcmm.16540