Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis

Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophag...

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Detalles Bibliográficos
Autores principales: Tao, Jun, Yang, Ping, Xie, Liqiu, Pu, Yuwei, Guo, Jiazhi, Jiao, Jianlin, Sun, Lin, Lu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184689/
https://www.ncbi.nlm.nih.gov/pubmed/33973365
http://dx.doi.org/10.1111/jcmm.16600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184689/
https://www.ncbi.nlm.nih.gov/pubmed/33973365
http://dx.doi.org/10.1111/jcmm.16600

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