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Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis
Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophag...
Autores principales: | Tao, Jun, Yang, Ping, Xie, Liqiu, Pu, Yuwei, Guo, Jiazhi, Jiao, Jianlin, Sun, Lin, Lu, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184689/ https://www.ncbi.nlm.nih.gov/pubmed/33973365 http://dx.doi.org/10.1111/jcmm.16600 |
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