RNA‐seq analysis of ageing human retinal pigment epithelium: Unexpected up‐regulation of visual cycle gene transcription

Ageing presents adverse effects on the retina and is the primary risk factor for age‐related macular degeneration (AMD). We report the first RNA‐seq analysis of age‐related transcriptional changes in the human retinal pigment epithelium (RPE), the primary site of AMD pathogenesis. Whole transcriptom...

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Detalles Bibliográficos
Autores principales: Butler, Joe M., Supharattanasitthi, Wasu, Yang, Yit C., Paraoan, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184696/
https://www.ncbi.nlm.nih.gov/pubmed/33934486
http://dx.doi.org/10.1111/jcmm.16569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184696/
https://www.ncbi.nlm.nih.gov/pubmed/33934486
http://dx.doi.org/10.1111/jcmm.16569

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