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Exosomes derived from MSC pre‐treated with oridonin alleviates myocardial IR injury by suppressing apoptosis via regulating autophagy activation

This study aimed to investigate the molecular mechanisms underlying the role of bone marrow mesenchymal stem cells (BMMSCs)‐derived exosomes in ischaemia/reperfusion (IR)‐induced damage, and the role of oridonin in the treatment of IR. Exosomes were isolated from BMMSCs. Western blot analysis was do...

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Detalles Bibliográficos
Autores principales: Fu, Minghuan, Xie, Dili, Sun, Ying, Pan, Yuanyuan, Zhang, Yunhe, Chen, Xiaohan, Shi, Yong, Deng, Shengnan, Cheng, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184716/
https://www.ncbi.nlm.nih.gov/pubmed/33955654
http://dx.doi.org/10.1111/jcmm.16558