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Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway

Oxytocin receptor (OXTR) is involved in social behaviors, thermoregulation, and milk ejection, yet little is known about its role in breast cancer. To investigate the role of OXTR in mammary gland development and tumorigenesis, a transgenic mouse model of OXTR overexpression ((++)Oxtr) was used. Ove...

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Detalles Bibliográficos
Autores principales: Li, Dan, San, Mingjun, Zhang, Jing, Yang, Anlan, Xie, Wanhua, Chen, Yang, Lu, Xiaodan, Zhang, Yuntao, Zhao, Mingyue, Feng, Xuechao, Zheng, Yaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184747/
https://www.ncbi.nlm.nih.gov/pubmed/34099636
http://dx.doi.org/10.1038/s41419-021-03849-8