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MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis

The effects of confounding factors on gene expression analysis have been extensively studied following the introduction of high-throughput microarrays and subsequently RNA sequencing. In contrast, there is a lack of equivalent analysis and tools for RNA splicing. Here we first assess the effect of c...

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Detalles Bibliográficos
Autores principales: Slaff, Barry, Radens, Caleb M., Jewell, Paul, Jha, Anupama, Lahens, Nicholas F., Grant, Gregory R., Thomas-Tikhonenko, Andrei, Lynch, Kristen W., Barash, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184769/
https://www.ncbi.nlm.nih.gov/pubmed/34099673
http://dx.doi.org/10.1038/s41467-021-23608-9