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Functional in vivo characterization of sox10 enhancers in neural crest and melanoma development

The role of a neural crest developmental transcriptional program, which critically involves Sox10 upregulation, is a key conserved aspect of melanoma initiation in both humans and zebrafish, yet transcriptional regulation of sox10 expression is incompletely understood. Here we used ATAC-Seq analysis...

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Detalles Bibliográficos
Autores principales: Cunningham, Rebecca L., Kramer, Eva T., DeGeorgia, Sophia K., Godoy, Paula M., Zarov, Anna P., Seneviratne, Shayana, Grigura, Vadim, Kaufman, Charles K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184803/
https://www.ncbi.nlm.nih.gov/pubmed/34099848
http://dx.doi.org/10.1038/s42003-021-02211-0