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Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibited longe...

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Detalles Bibliográficos
Autores principales: Komura, Tomomi, Yamanaka, Mikihiro, Nishimura, Kohji, Hara, Keita, Nishikawa, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184826/
https://www.ncbi.nlm.nih.gov/pubmed/34099724
http://dx.doi.org/10.1038/s41514-021-00061-y