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Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans
To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibited longe...
Autores principales: | Komura, Tomomi, Yamanaka, Mikihiro, Nishimura, Kohji, Hara, Keita, Nishikawa, Yoshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184826/ https://www.ncbi.nlm.nih.gov/pubmed/34099724 http://dx.doi.org/10.1038/s41514-021-00061-y |
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