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Single-cell RNA sequencing of human nail unit defines RSPO4 onychofibroblasts and SPINK6 nail epithelium

Research on human nail tissue has been limited by the restricted access to fresh specimen. Here, we studied transcriptome profiles of human nail units using polydactyly specimens. Single-cell RNAseq with 11,541 cells from 4 extra digits revealed nail-specific mesenchymal and epithelial cell populati...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Je, Shim, Joon Ho, Park, Ji-Hye, Shin, Hyun Tae, Shim, Jong Sup, Jang, Kee-Taek, Park, Woong-Yang, Lee, Kyung-Hoon, Kwon, Eun Ji, Jang, Hyung-Suk, Yang, Hanseul, Lee, Jong Hee, Yang, Jun-Mo, Lee, Dongyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184830/
https://www.ncbi.nlm.nih.gov/pubmed/34099859
http://dx.doi.org/10.1038/s42003-021-02223-w