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Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner

Hyaluronan (HA) cross-linking is a conformational state of HA, a covalent complex between HA and heavy chains (HCs) from inter-α-trypsin inhibitor (I-α-I) mediated by tumor necrosis factor-induced protein 6 (TSG6). Cross-linked HA has been identified as a protective factor in physiological and infla...

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Detalles Bibliográficos
Autores principales: Zhang, Guoliang, He, Yiqing, Liu, Yiwen, Du, Yan, Yang, Cuixia, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184848/
https://www.ncbi.nlm.nih.gov/pubmed/34099638
http://dx.doi.org/10.1038/s41419-021-03875-6