Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair

The versatile nucleotide excision repair (NER) pathway initiates as the XPC–RAD23B–CETN2 complex first recognizes DNA lesions from the genomic DNA and recruits the general transcription factor complex, TFIIH, for subsequent lesion verification. Here, we present a cryo-EM structure of an NER initiati...

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Detalles Bibliográficos
Autores principales: van Eeuwen, Trevor, Shim, Yoonjung, Kim, Hee Jong, Zhao, Tingting, Basu, Shrabani, Garcia, Benjamin A., Kaplan, Craig D., Min, Jung-Hyun, Murakami, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184850/
https://www.ncbi.nlm.nih.gov/pubmed/34099686
http://dx.doi.org/10.1038/s41467-021-23684-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184850/
https://www.ncbi.nlm.nih.gov/pubmed/34099686
http://dx.doi.org/10.1038/s41467-021-23684-x

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