Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function

B10 cells are regulatory B cells capable of producing IL-10 for maintaining immune homeostasis. Dysregulation of B10 cells occurs in autoimmune and inflammatory diseases. Modulation or adoptive transfer of B10 cells is a promising therapeutic strategy. The short-chain fatty acids (SCFAs), the metabo...

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Detalles Bibliográficos
Autores principales: Zou, Fagui, Qiu, Yi, Huang, Yilian, Zou, Hang, Cheng, Xiao, Niu, Qingru, Luo, Aoxiang, Sun, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184914/
https://www.ncbi.nlm.nih.gov/pubmed/34099635
http://dx.doi.org/10.1038/s41419-021-03880-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184914/
https://www.ncbi.nlm.nih.gov/pubmed/34099635
http://dx.doi.org/10.1038/s41419-021-03880-9

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