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Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles

Hyperlipidemia, the hallmark of Metabolic Syndrome that afflicts millions of people worldwide, exacerbates life-threatening infections. We present a new evidence for the mechanism of hyperlipidemic hypersensitivity to microbial inflammation caused by pathogen-derived inducer, LPS. We demonstrate tha...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Zienkiewicz, Jozef, Boyd, Kelli L., Smith, Taylor E., Xu, Zhi-Qi, Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184916/
https://www.ncbi.nlm.nih.gov/pubmed/34099795
http://dx.doi.org/10.1038/s41598-021-91395-w