GATA3 induces mitochondrial biogenesis in primary human CD4(+) T cells during DNA damage

GATA3 is as a lineage-specific transcription factor that drives the differentiation of CD4(+) T helper 2 (Th2) cells, but is also involved in a variety of processes such as immune regulation, proliferation and maintenance in other T cell and non-T cell lineages. Here we show a mechanism utilised by...

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Detalles Bibliográficos
Autores principales: Callender, Lauren A., Schroth, Johannes, Carroll, Elizabeth C., Garrod-Ketchley, Conor, Romano, Lisa E. L., Hendy, Eleanor, Kelly, Audrey, Lavender, Paul, Akbar, Arne N., Chapple, J. Paul, Henson, Sian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184923/
https://www.ncbi.nlm.nih.gov/pubmed/34099719
http://dx.doi.org/10.1038/s41467-021-23715-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184923/
https://www.ncbi.nlm.nih.gov/pubmed/34099719
http://dx.doi.org/10.1038/s41467-021-23715-7

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